In Regard to Rahman et al

Varian is writing this response to Rahman et al1Rahman al.Electron FLASH delivery at treatment room isocenter for efficient reversible conversion of a clinical LINAC.Int J Radiat Oncol Biol Phys. 2021; 110: 871-881Abstract Full Text PDF Scopus (18) Google Scholar express concern over modifying linear accelerators (LINACs) perform research and then restoring those same LINACs use, as described in their article. engineers have analyzed the proposed LINAC modifications determined that continued use such modified devices presents significant potential patient harm. Hazards may arise from human error properly use. concerned about unpredictable, unintended consequences when untrained users manually modify complex systems. The Clinac system was neither designed nor tested reliably detect modifications, quality assurance procedures not all errors configuration. Additionally, with by authors, portions would be operated dose rates beyond which or tested. This could cause equipment damage degradation result mistreatment, reduced operating life system, failures requiring expensive replacements repair. cannot guarantee safety effectiveness systems modified, operated, later restored manner article al. We recommend against user responsible any mistreatment resulting conversions. strongly recommends conversions done only on decommissioned machines returned Service must notified so these can designated nonclinical Varian's service medical device history records. Although encourages FLASH, it vital conducted ensure patients. user-modified should Customers reach out regarding conditions electron programs support.